Palladium catalyzed regioselective B–C(sp) coupling via direct cage B–H activation: synthesis of B(4)-alkynylated o-carboranes
نویسندگان
چکیده
منابع مشابه
Palladium catalyzed regioselective B–C(sp) coupling via direct cage B–H activation: synthesis of B(4)-alkynylated o-carboranes
Pd-catalyzed carboxylic acid guided regioselective alkynylation of cage B(4)–H bonds in o-carboranes has been achieved for the first time using two different catalytic systems. In the presence of 5 mol% Pd(OAc)2 and 3 equiv. of AgOAc, the reaction of 1-COOH-2-R-C2B10H10 with R3SiC^CBr in ClCH2CH2Cl gives 4(R3SiC^C)-2-R -o-C2B10H10 in moderate to high yields. This reaction is compatible with alk...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2016
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c6sc00901h